منابع مشابه
Thioridazine hydrochloride
Major uses Thioridazine hydrochloride (further thioridazine) is a representative of phenothiazine compounds, and it is an antipsychotic drug (synthesized in 1959). It relieves tension and anxiety, and acts against multiple symptoms, e.g. agitation, depression, behavior problems and sleep disturbances. Thioridazine is also effective in controlling the symptoms of schizophrenia, mania, and other ...
متن کاملEffect of Thioridazine on Erythrocytes
BACKGROUND Thioridazine, a neuroleptic phenothiazine with antimicrobial efficacy is known to trigger anemia. At least in theory, the anemia could result from stimulation of suicidal erythrocyte death or eryptosis, which is characterized by cell shrinkage and by phospholipid scrambling of the cell membrane with phosphatidylserine exposure at the erythrocyte surface. Triggers of eryptosis include...
متن کاملVoltammetric Determination of Thioridazine Hydrochloride
Thioridazine hydrochloride, a member of the phenothiazine group, is one of the most widely used drugs in the treatment of psychiatric patients. It has a tranquilizing effect, but no therapeutically significant anti-emetic or hypothermic effect, which other phenothiazine drugs have, and does not potentiate the action of anestetics. Thioridazine is used mainly in the treatment of schizophrenia an...
متن کاملThioridazine (Melleril) retinopathy.
The drug thioridazine was first introduced in I959 and Weekley, PQtts, Reboton, and May (I960) reported the first cases of pigmentary retinopathy, in four patients who had been given approximately 2 g. daily for 30-50 days. The manufacturers (Sandoz) subsequently recommended that a daily dose of 8oo mg. should not be exceeded and since then only about half a dozen articles have appeared (all in...
متن کاملElectron microscopic observation of thioridazine-induced hepatitis.
The introduction of new drugs for clinical practice in recent years, has caused an increasing number of drug-induced hepatic injuries, which are currently receiving much attention because of their iatrogenic nature . As one of the approaches to the study of pathogenesis, electron microscopic studies have been undertaken. This report is concerned with an electron microscopic observation of the l...
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ژورنال
عنوان ژورنال: BMJ
سال: 2002
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.325.7370.967/a